UkrLabsInstrumental Laboratory
NSF OTAVA
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Completed study

Does a plant extract match the material stated on the label?

We compared a reference nettle root sample with two batches from suppliers using their chemical profiles.

About plant material testing →
Chromatograms of a reference nettle root sample and two supplier batches
Study chromatograms: a reference nettle root sample and two supplier batches.

A dietary supplement label may name a plant. But once the material has been ground and made into an extract, you cannot identify it by appearance. We therefore compare the sample's chemical composition with verified plant material used as a reference.

How we compare samples

We use high-performance liquid chromatography–mass spectrometry (HPLC–MS). The analysis produces a chemical profile: a pattern of signals that can be compared with a reference material. We are building a database of these profiles. It currently covers more than 35 species of medicinal plants used in Ukraine and continues to grow.

Example: nettle roots

We prepared an extract from a collected reference sample and compared it with two batches from suppliers. The three chromatograms were similar, and the corresponding mass spectrometry signals also matched.

Nettle root chromatograms: reference material and two supplier batches. The colored lines show the results for the three samples.
Overlaid chromatograms for a reference nettle root sample and two supplier batches

These results indicate that the tested batches are consistent with the chosen reference sample. This comparison can help check plant material before production.

Our next step is to expand the reference database and assess how well this approach works for complex extracts and finished dietary supplements, including mixtures of several plant extracts.

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