Анатолій Баланда, к.х.н.

Патенти:

  1. Pat. 86041, 10.12.2013. Low-molecular organic ATP-competitive inhibitors of serine/threonine kinase CK2 based on 4-aminothieno-[2,3-d]pyrimidine heterocycle. Ostrynska OV, Balanda AO, Bdzhola VG, Kotey IM, Kukharenko OP, Yarmoluk SM.
  2. Pat. WO2011/065980 (A2), 03.06.2011. Dyes for Analysis of Protein Aggregation. Patton WF; Yarmoluk SM; Pande P; Kovalska V; Dai L; Volkova K; Coleman L; Losytskyy M; Ludlam A; Balanda A; Shen D.

Публікації:

  1. Ostrynska OV, Balanda AO, Bdzhola VG, Golub AG, Kotey IM, Kukharenko OP, Gryshchenko AA, Briukhovetska NV, Yarmoluk SM (2016) Design and synthesis of novel protein kinase CK2 inhibitors on the base of 4-aminothieno[2,3-d]pyrimidines. Eur J Med Chem 115:148-160.
  2. Gryshchenko AA, Bdzhola VG, Balanda AO, Briukhovetska NV, Kotey IM, Golub AG, Ruban TP, Lukash LL, Yarmoluk SM (2015) Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1. Bioorg Med Chem 23(9):2287-2293.
  3. Gryshchenko AA, Bdzhola VG, Balanda AO, Lukashov SS, Fesun IM, Yarmoluk SM (2012) Inhibitors of protein kinase FGFR1 from phenylhydrazine class. Ukrainica Bioorganica Acta 1:48-50.
  4. Golub AG, Bdzhola VG, Briukhovetska NV, Balanda AO, Kukharenko OP, Kotey IM, Ostrynska OV, Yarmoluk SM (2011) Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem 46(3):870-876.
  5. Tokar VP, Losytskyy MYu, Ohulchanskyy TY, Kryvorotenko DV, Kovalska VB, Balanda AO, Dmytruk IM, Yashchuk VM, Yarmoluk SM (2010) Styryl dyes as two-photon excited fluorescent probes for DNA detection and two-photon laser scanning fluorescence microscopy of living cells. J Fluoresc 20(4):865-872.
  6. Volkova KD, Kovalska VB, Balanda AO, Slominskii YuL, Tolmachev OI, Subramaniam V, Yarmoluk SM (2008) Studies of mono- and trimethine cyanine dyes as specific fluorescent probes for fibrillarβ-lactoglobulin detection. Ukrainica Bioorganica Acta 6(2):15-21.
  7. Kotey IM, Balanda AO, Bdzhola VG, Lukashov SS, Kukharenko OP, Kharchenko VM, Yarmoluk SM (2008) Synthesis and biologic evaluation of thienopyrimidinones inhibition activity against protein kinase CK2. Ukrainica Bioorganica Acta 6(2):3-9.
  8. Volkova KD, Kovalska VB, Balanda AO, Losytskyy MYu, Golub AG, Vermeij RJ, Subramaniam V, Tolmachev OI, Yarmoluk SM (2008) Specific fluorescent detection of fibrillar α-synuclein using mono- and trimethine cyanine dyes. Bioorganic and Medicinal Chemistry 16(3):1452-1459.
  9. Akbay N, Losytskyy MYu, Kovalska VB, Balanda AO, Yarmoluk SM (2008) The mechanism of benzothiazole styrylcyanine dyes binding with dsDNA: studies by spectral-luminescent methods. Journal of Fluorescence 18(1):139-147.
  10. Volkova KD, Kovalska VB, Balanda AO, Vermeij RJ, Subramaniam V, Slominskii YuL, Yarmoluk SM (2007) Cyanine dye-protein interactions: looking for fluorescent probes for amyloid structures. Journal of Biochemical and Biophysical Methods 70(5):727-733.
  11. Yashchuk VM, Gusak VV, Dmytruk IM, Prokopets VM, Kudrya VYu, Losytskyy MYu, Tokar VP, Gumenyuk YaO, Yarmoluk SM, Kovalska VB, Balanda AO, Kryvorotenko DV (2007) Two-photon excited luminescent styryl dyes as probes for the DNA detection and imaging. Photostability and phototoxic influence on DNA.Molecular Crystals and Liquid Crystals 467(1):325-338.
  12. Yashchuk VM, Kudrya VYu, Losytskyy MYu, Tokar VP, Yarmoluk SM, Dmytruk IM, Prokopets VM, Kovalska VB, Balanda AO, Kryvorotenko DV, Ogul'chansky TYu (2007) The optical biomedical sensors for DNA detection and imaging based on two-photon excited luminescent styryl dyes: phototoxic influence on the DNA.SPIE 6796
  13. Losytskyy MYu, Akbay N, Kovalska VB, Balanda AO, Boutorine A, Yarmoluk SM (2007) To the studies of (p-dimethylaminostyryl)pyridinium based homodimer to dsDNA binding mechanism. Ukrainica Bioorganica Acta 5(2):52-55.
  14. Balanda AO, Volkova KD, Kovalska VB, Losytskyy MYu, Tokar VP, Prokopets VM, Yarmoluk SM (2007) Synthesis and spectral-luminescent studies of novel 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]thieno[2,3-d]pyrimidinium styryls as fluorescent dyes for biomolecules detection. Dyes and Pigments 75(1):25-31.
  15. Balanda AO, Volkova KD, Kovalska VB, Tokar VP, Yarmoluk SM (2006) Synthesis and spectral studies of styrylcyanines based on 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]thieno[2,3-d]pyrimidinium and 5-oxo-1,2,3,5-tetrahydropyrrolo[2,1-b]quinazolinium. Ukrainica Bioorganica Acta 4(2):10-15.
  16. Kovalska VB, Volkova KD, Losytskyy MYu, Tolmachev OI, Balanda AO, Yarmoluk SM (2006) 6,6'-Disubstituted benzothiazole trimethine cyanines – new fluorescent dyes for DNA detection. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 65(2):271-277.
  17. Tokar VP, Losytskyy MYu, Kovalska VB, Kryvorotenko DV, Balanda AO, Prokopets VM, Galak MP, Dmytruk IM, Yashchuk VM, Yarmoluk SM (2006) Fluorescence of styryl dyes-DNA complexes induced by single- and two-photon excitation. Journal of Fluorescence 16(6):783-791.
  18. Kovalska VB, Losytskyy MYu, Kryvorotenko DV, Balanda AO, Tokar VP, Yarmoluk SM (2006) Synthesis of novel fluorescent styryl dyes based on the imidazo[1,2-a]pyridinium chromophore and their spectral-fluorescent properties in the presence of nucleic acids and proteins. Dyes and Pigments 68(1):39-45.
  19. Kovalska VB, Kocheshev IO, Kryvorotenko DV, Balanda A, Yarmoluk SM (2005) Studies on the spectral-luminescent properties of the novel homodimer styryl dyes in complexes with DNA. Journal of Fluorescence 15(3):215-219.
  20. Kovalska VB, Kryvorotenko DV, Balanda AO, Losytskyy MYu, Tokar VP, Yarmoluk SM (2005) Fluorescent homodimer styrylcyanines:synthesis and spectral-luminiscent stidies in nucleic acids and protein complex. Dyes and Pigments 67(1):47-54.
  21. Nizamov NN, Ismailov ZF, Kurtaliev EN, Nizamov ShN, Khaydarova FU, Khodjayev G, Kukharenko OP, Balanda AO, Yarmoluk SM (2005) Toxicity evaluation of the series of cyanine dyes used for nucleic acids and proteins detection. Ukrainica Bioorganica Acta 3(2):35-38.
  22. Kryvorotenko DV, Losytskyy MYu, Balanda AO, Yarmoluk SM (2000) Proteins and cyanine dyes. IV. Benzothiazol-4-[2,6-dimethylpyridinium] monomethine cyanine dyes for homogeneous detection of proteins.Vistnyk of “Lvivs'ka Politechnika” University – Chemistry 414:127-135.
  23. Yarmoluk SM, Kryvorotenko DV, Balanda AO, Losytskyy MY, Kovalska VB (2001) Proteins and cyanine dyes. Part III. Synthesis and spectroscopic studies of benzothiazolo-4-[1,2,6-trimethylpyridinium] monomethine cyanine dyes for fluorescent detection of bovine serum albumin in solutions. Dyes and Pigments 51(1):41-49.
  24. Yarmoluk SM, Kovalska VB, Kryvorotenko DV, Balanda AO, Ogul'chansky TYu (2001) Interaction of cyanine dyes with nucleic acids. XXV. Influence of affinity-modifying groups in the structure of benzothiazol-4-[2,6-dimethylpyridinium] dyes on the spectral properties of the dyes in the presence of nucleic acids.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 57(7):1533-1540.