Vladyslava Kovalska, Dr.Sci.
Leading Scientific Researcher
Leading Scientific Researcher. She graduated Chemical Faculty of Kiev Taras Shevchenko National University. In 1996-1999 Vladyslava performed PhD studies in Institute of Molecular Biology and Genetics of NAS of Ukraine. Also starting from 1996 she is employee of Institute. In 2000 Vladyslava obtained Ph.D degree in molecular biology, in 2012 – Doctor of Science degree (Dr.hab.) in biology. Now Vladyslava works in Biomedical Chemistry Department of the Institute and is Leader of Fluorescent Probes Design Group.
Vladyslava is co-author of 78 papers in scientific journals, 4 international patents and applications, 2 chapters in books.
Vladyslava’s main researcher areas are development of fluorescent probes for detection of biopolymers – protein amyloid fibrils, native proteins and nucleic acids, study of inhibitory activity of macrocyclic compounds in amyloid aggregation of proteins, characterization of interaction between macrocyclic metal complexes with globular proteins by spectral-luminescent techniques.
Volodymyr Bdzhola, Ph.D.
Senior Scientific Researcher
Dr. Bdzhola received his M.S. degree from National Taras Shevchenko University of Kyiv, Ukraine in 1994. In 1998 he awarded the degree of Ph.D. in Inorganic Chemistry. Since 2001 to present time he works at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine.
Dr. Bdzhola is a co-author of 144 publications and 6 patents.
Currently, his research is in the field of rational design of enzyme inhibitors. He has extensive experience in the development of small-molecular inhibitors for human protein kinases CK2 (casein kinase 2), ASK1 (apoptosis signal-regulating kinase 1), FGFR1 (fibroblast growth factor receptor 1), and, also, for several polymerases and aminoacyl-tRNA synthetases. Bioinformatics, chemoinformatics tools, docking and molecular dynamics approaches are used in his study for in silico design of enzyme inhibitors.
Anatoliy Balanda, Ph.D.
Dr. Balanda received his M.S. degree from National Taras Shevchenko University of Kyiv, Ukraine in 2000. Since that year he works at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine. In 2007 he awarded the degree of Ph.D. in Bioorganic Chemistry under supervision of Prof. Sergiy Yarmoluk.
Dr. Balanda is a co-author of 45 scientific publications and 2 patents. Currently, his research is in the field of chemical synthesis of protein kinase inhibitors as potential anti-cancer drugs. Also, he is involved in the Projects dedicated to the development of fluorescent dyes for detection of protein aggregation.
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