Molecular Phylogenetics

Laboratory of Biosynthesis of Nucleic Acids

Published date: 
Feb 12, 2015
Research Services: 

Bioinformatics

  • Analysis of differential gene expression (DGE) using publicly available databases;
  • Microarray and next generation sequencing data analysis;
  • Gene expression clustering;
  • Kohonen’s maps
  • Gene and protein sequence analysis and alignment;
  • Phylogenetic and evolutionary studies;
  • Homology modeling;
  • Anti-sense oligos and primers design.

Other services

Laboratory of Computer Modeling

Published date: 
Jan 30, 2015
Research Services: 
  • Virtual high-throughput screening using structure-based (molecular docking) and ligand-based (QSAR, pharmacophore modeling) approaches;
  • Identification and analysis of binding sites;
  • Structure-activity relationship (SAR) analysis;
  • Computational studies of drug-receptor interactions;
  • Hit identification and optimization;
  • Hit to lead optimization;
  • In silico ADME predictions;
  • Molecular dynamics of proteins, nucleic acids, extra large heterogeneous systems;
  • Design of target-focused compound libraries with high affinity to the molecular targets (our compound collection contains about 200,000 organic compounds which are immediately available for screening).